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NSAID Survivors
 
 
 
 

"Herbie"

I'm just glad I knew what to look for........

In August of 2003 was our first experience with Deramaxx. Herbie was a 4 yr old Miniature Pinscher that presented with a leg issue. He was favoring his right rear leg and pulling up quite a bit. Our vet wanted to try crate rest and some Deramaxx for a soft tissue injury. We started the Deramaxx with no sign of improvement after a week. I had read the side effects so I'd know what to look for and so far nothing appeared. The vet wanted to try another round. Into the second week, Herbie started having blood in his stool. It happened to be on a Sunday and the vet's office was closed so I called the local ER. I told them that he was on the Deramaxx and they ordered me to stop giving it to him immediately and if the blood did not clear to get him there as soon as possible. Lucky for us that was his only sign of trouble during his treatment. We have it noted in his files that he is sensitive to NSAIDs and will never be given another one again. I don't know about long term effects from his short usage but he does have stomach issues from time to time.

I'm just glad I knew what to look for and made it a point to check his stool every time. If I had not, it could have been much worse. As for Herbie's leg, FHO surgery in October of 2003 took care of the pain and he's 99% on the leg these days.

Tina & Crew
http://www.geocities.com/ownedbyminpins
Min Pins Annie, Herbie, Twiggie & Papillon Cooper
CD, CDX, ASCA-CD, CGC, TT

 

 

"Quincy"

We believed if our dog had to have surgery, Cornell certainly was the best place to do that.

 

We believe sometime in December Quincy blew out his knee on ice and we took him to our local vet to see what the situation was. They x-rayed him and said he had a ruptured cruciate. They said they could do the surgery there, but suggested a sturdier surgery for dogs 80 lbs and over. This "TPLO" was to be done at Cornell. We believed if our dog had to have surgery, Cornell certainly was the best place to do that. Quincy was prescribed Etogesic by our vet for the pain prior to the surgery. You should also know that Quincy has hip dsyplasisa and was diagnosed approximately 4 years ago at age 2. We would give him it very infrequently. He would have a flair up once a month, and would take it for only one day during his flair up. Now, with his bad knee he was taking it daily for 3 weeks straight as diagnosed by our vet. I should make it clear that we are very happy with our vet and do not believe he is at all the problem.

Don and I took him in to Cornell and they required their own set of X-rays. The gave him a light sedative and reviewed his X-rays and suggested the TPLO would be a good match for Quincy. The next day (Tuesday) they performed the surgery and we were called in the evening and he was doing well. After surgery he was given hydromorphone for pain and a fentanyl patch.

By Wednesday morning things took a very horrible turn. Quincy was throwing up 2 liters of blood was tachycardic with episodes of ventricular premature contractions. Quincy was then moved to ICU. He was given plasma transfusions, and other medications to help nausea and vomiting. He was also given some sort of drip to help reduce pain. Assessments showed his placked cell volume of 22% and a total protein of 2.8. A CBC done revealed the same anemia and low total protein. I could go into more detail, but there is simply too much.

There were two episodes were we thought we had lost him.

On Thursday they performed an endoscopy which revealed severe and diffuse erosions of his gastric mucosa as well as severe esophagitis. One of the veterinarians there said it was the worse case he had ever seen, which should give you some indication of how bad it was. He was given more packed red blood cells, and a unit of plasma. The surgery on his knee had certainly became secondary. While all this was going on I did some research on my own and found instances where this occurred.

Quincy stayed at Cornell for 12 days in ICU. Don and I believe what occurred was a result of horrible side effects of his taking Etogesic. Our local vet has let Fort Dodge Animal Health know of what occurred and has a copy of the transcripts from Cornell of what happened every single day. We also have a case number with Fort Dodge Animal Health.

In the transcripts provided by Cornell it states the following "Unfortunately, we are unable to pinpoint with certainty, cause for Quincy's GI erosions. NSAIDs have the potential to cause ulceration (usually focal) especially when used in combination with Steroids. Although Quincy was on a low dose of etogesic, every dog acts as an individual, and he may have hypersensitivity to it".

Speaking personally, I think it will be difficult for Fort Dodge to deny as it is coming from the top vet school in the country, that Etogesic played a significant role in this horrible incident. You may be interested to know that in the instruction portion of the summary from Cornell they state the following, "It is difficult to determine the cause of Quincy's gastric mucosal erosions. Since we are unable to rule out the potential role NSAIDs (like etogesic) may have played in his condition, we recommend avoiding the use of NSAIDs to control any pain Quincy may have in the future". This I believe is pretty telling.

Along with a 12 day stay in Cornell, and a $6,700 vet bill, Quincy is home and doing well. I hope this story will serve as some inspiration for those who are going through it now, that there is hope, and a warning for those who are considering giving their pets Etogesic or any NSAIDs.

Don and I believe if this happened in any other vet clinic he would have not made it. With the technology, skill, and the collective knowledge they have at their fingertips he pulled through. My husband and I lost several days at work so we could be there for Quincy, and those 12 days were an emotional roller coaster for us.

I hope this helps out in any way at all.

Thanks for sharing our story with those who may benefit by it.


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